1. Name: David Guerra Aragão

Nacionality: Portuguese

Birth: January 1976

2. Address

Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Avenida da República, P-2784-505, Oeiras, Portugal
Telephone: + 315 214469668 ; Fax : 351-2143 3644 ; e-mail: David Arag„o
URL: http://www.itqb.unl.pt


ESRF, Sector 14, room 14-1-16, B.P. 220, F-38043 Grenoble, France.
Telephone: +33 (0) 47688-2892 ; e-mail: e-mail: David Aragao
URL: http://www.esrf.fr

3. Academic Degrees

2000- Graduated in Organic Chemistry by Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Portugal (http://www.fct.unl.pt)

4. Present Academic Position

Doing studies to obtain a Ph. D. in Molecular Biology and Protein Crystallography, since January 2002.
Thesis Title: “Structure to Function Studies in Hybrid Cluster Proteins”

5. Other Positions:

2004 – In the Organization of the friday SCAN seminars at ITQB/UNL.
2002/2003 – Representative of the Ph. D. students in the Universidade Nova de Lisboa General Assembly.

6. Research Interests:

Protein expression, purification and structure determination by crystallographic studies of iron-sulphur proteins in ??Pathogens.??

8. Honours:

2004 – One of the 12 winners in a contest by Amersham Biosciences to produce a figure for the 2004 Amersham Calendar (won the month of February with a picture of the Hybrid Cluster Protein – HCP)
2003 - Figure of HCP in the Cover of JBIC 2003
2000 - 3rd best student finishing his degree

9. Other activities:

Member of the webpage group of the Portuguese Student Researchers Association / Associação dos Bolseiros de Investigação Cientifica. (http://www.abic.org).

10. Publications:

1.S. Macedo, D. Aragão, E. P. Mitchell and P. Lindley . “Structure of the hybrid cluster protein (HCP) from Desulfovibrio desulfuricans ATCC 27774 containing molecules in the oxidized and reduced states” Acta Cryst. (2003). D59, 2065-2071

2.Aragão D, Macedo S, Mitchell EP, Romao CV, Liu MY, Frazao C, Saraiva LM, Xavier AV, LeGall J, van Dongen WM, Hagen WR, Teixeira M, Carrondo MA, Lindley P. ”Reduced hybrid cluster proteins (HCP) from Desulfovibrio desulfuricans ATCC 27774 and Desulfovibrio vulgaris (Hildenborough): X-ray structures at high resolution using synchrotron radiation. J Biol Inorg Chem. 2003 May;8(5):540-8. Epub 2003 Feb 15.

3.Aragão D, Frazao C, Sieker L, Sheldrick GM, LeGall J, Carrondo MA. “ Structure of dimeric cytochrome c3 from Desulfovibrio gigas at 1.2 A resolution.”Acta Crystallogr D Biol Crystallogr. 2003 Apr;59(Pt 4):644-53

4.Aragao D, Marques AR, Frazao C, Enguita FJ, Carrondo MA, Fialho AM, Sa-Correia I, Mitchell EP. “Cloning, expression, purification, crystallization and preliminary structure determination of glucose-1-phosphate uridylyltransferase (UgpG) from Sphingomonas elodea ATCC 31461 bound to glucose-1-phosphate. ”Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 Sep 1;62(Pt 9):930-4